Why Repair
Aortic Insufficiency?

Growing Evidence for Aortic Valve
Repair vs. Replacement

Why Repair
Aortic Insufficiency?

Growing Evidence for Aortic Valve
Repair vs. Replacement

Improved Survival

at 8 years (1, 2)

Reduced Adverse Events

at 10 years (3)

See The Growing Evidence for

Aortic Valve Repair

Improved Survival

at 8 years (1, 2)

Reduced Adverse Events

at 10 years (3)

See The Growing Evidence for

Aortic Valve Repair

Propensity Match Studies

Studies highlight improved survival and lower cardiac event rates with aortic valve repair vs. valve replacement for Aortic Insufficiency

Improved Survival at 8 years

100% vs. 88.9% (p=0.025)

Similar reoperation rates, no signifcant difference
9.1 % vs. 3.3% (p=0.97)

Northwestern University

1) Malaisrie SC, et al. Valve-sparing versus valve-replacing aortic root
replacement in patients with aortic root aneurysm. J Card Surg. 2022 Apr 5.

Improved Survival at 8 years

87% vs. 60% (p=0.007)

Similar reoperation rates, no signifcant difference
8% vs. 2% (log rank P=0.35)

Universite Catholique de Louvain, Belgium

2) de Meester C, et al. Valve repair improves the outcome of surgery for chronic severe aortic regurgitation: a propensity score analysis.
J ThoracCardiovasc 5urg. 2014 Nov;l 48(5):1913-20.

Greater Event-free
Survival at 10 years

82% vs. 68% (p=0.024)

Similar reopareation rates, no significant difference
7% vs. 3% (p=0.44)

University of Ottawa Heart Institute

3) Jabagi H, et al. Aortic Valve Repair Decreases Risks ofVRE in Al at 10 Years: A Propensity Score-Matched Analysis. Ann ThoracSurg. 2021 Jul 3:50003-4975(21 )01165-6.

Getting Started with Aortic Valve Repair

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PATIENT YEARS OF DATA

Organizations Contributing to the Aortic Valve Repair Experiences

AHA/ACC Guidelines
Repair is Required at “Level I” Centers

Requirement for Level 1 Comprehensive Valve Centers

The 2020 ACC/AHA Guidlines for Valvular Heart Disease reinforce the role of aortic valve repair in Comprehensive (Level 1) Valve Centers and outline the or many indications for repair.

Chronic Severe AR: Isolated or with concomitant procedures

Moderate AR: with concomitant procedures

Aneurysm: Root and Ascending Aortic Aneurysm

Bicuspid Aortic Valve Disease with AR

See the latest aortic valve repair techniques and the broad range of applications

EU Guidelines

Recognizing Benefits of Repair

Highlight good long-term results and lower valve related events with Aortic Valve Repair

The 2021 ESC/EACTS Guidelines for Aortic Regurgitation recognize the benefits for aortic valve repair vs. replacement. The guidelines recognize the results of expert centers and surgeons with aortic valve repair experience.

Valve-sparing procedures have a Class I recommendation for young patients with aortic root dilatation, when performed in experienced centers.

Survival Rate, Cardiac Event Rate and

Repair Failure Rate

Improved Survival at 8 years

Improved Survival at 8 years

Greater Event-free

 

Survival at 10 years