Internal Aortic Annuloplasty

Restoring the normal annular geometry

The HAART 300 Aortic Annuloplasty Devices replicate normal annular anatomy. The devices are designed to:

  • reduce & prevent annular dilatation
  • restore three-dimensional annular geometry
  • serve as a framework to guide leaflet repair[1]

Designed for the 3D Aortic Annulus

Based on normal, healthy valve geometry

High resolution, CT angiogram images of normal aortic valves with good leaflet coaptation were the basis of the HAART 300 design.[2] Native aortic valves were found to have an elliptical base geometry and three outwardly flaring commissures.

Computed Tomographic Angiograms (CTA)

HAART 300 Devices Replicate Normal Annular Anatomy

Ensuring annulus is sized for good leaflet coaptation

  • Elliptical base with a 2:3 minor-to-major axis ratio
  • Three outwardly flaring posts spaced equally around the base circumference

Applying Carpentier principles of
annuloplasty + leaflet reconstruction
to the Aortic Valve

HAART 300 Aortic Annuloplasty Device topview
HAART 300 Aortic Annuloplasty Device - sideview

Simple & Standardized Annuloplasty Technique

Sizing – Innovative & Accurate

Determined from leaflet free-edge length to ensure good coaptation

Device Placement

Post & Looping sutures to ensure stable device to annulus fixation

Accurate Leaflet Based Sizing

Leaflet free-edge measurements determine the normal annular dimension for improved leaflet coaptation

No Deep Root Dissection

Save time and avoid the deep root dissection and coronary reimplantation when not indicated

Standardized Leaflet Repairs

Devices recruit the leaflets towards the midline and provide a stable base for reproducible leaflet reconstruction

Rapidly Expanding Clinical Evidence & Experience

HAART 300 Clinical Trial

The multi-center, 65 patient, HAART 300 clinical trial provides strong evidence of the potential safety and efficacy of the HAART 300 device.[3]

  • Low morbidity, no in-hospital mortality
  • 95% survival at mean 2 year follow-up
  • Mean gradient of 9.4 mm Hg and valve areas of 2.7 cm2
  • Significant improvement in AI grade and NYHA class
HAART 300 Clinical Trial

Peer Reviewed Publications

Trained Surgeons

Trained Centers

  1. Crooke PS, et al. Design Characteristics of a Three-Dimensional Geometric Aortic Valve Annuloplasty Ring. Innovations 2013;8:364-370.
  2. Rankin JS, et al. A refined hemispheric model of normal human aortic valve and root geometry. J Thorac Cardiovasc Surg. 2013 Jul;146(1):103-108.
  3. Mazzitelli D, et al. Geometric ring annuloplasty as an adjunct to aortic valve repair: clinical investigation of the HAART 300 device. Eur J Cardiothorac Surg 2016;49:987–93.