Aortic valve repair for tri-leaflet aortic insufficiency associated with asymmetric aortic root aneurysms

Article in the Annals of Cardiothoracic Surgery.

Aortic valve repair for tri-leaflet aortic insufficiency associated with asymmetric aortic root aneurysms

Stavridis GT, Downey RS, Gerdisch MW, Hughes GC, Jasinski MJ, Rankin JS, Mazzitelli D, Aicher D, Fischlein T, Choi YH, Weber A, Friedrich I, Glauber M, Pfeiffer S, Miceli A, Si MS, Klokocovnik T, Wei LM, Deja MA, Badhwar V. Aortic valve repair for tri-leaflet aortic insufficiency associated with asymmetric aortic root aneurysms. Ann Cardiothorac Surg 2019;8(3):426-429. doi: 10.21037/acs.2019.04.10

Clinical Vignette
The patient was a 47-year-old male with mild heart failure and an expanding 5.2-cm ascending aortic aneurysm. His sinuses also were involved, with a 6.3-cm aortic root diameter. He had Grade 4 aortic insufficiency (AI) (Figure 1) and his left ventricle and coronaries were normal. His aortic annulus was especially dilated at 30 mm. The right and non-coronary sinuses were primarily involved in the root aneurysm and his left sinus seemed normal. Echocardiography showed the dilated annulus, leaflet tethering from the sinotubular junction (STJ) dilatation and normal appearing leaflets. The AI was central and severe with stretching of the leaflets and loss of central coaptation. No leaflet prolapses or other defects were evident. […] [Read the entire article.]

Early results for HAART 200 and HAART 300 with Dr. Joseph Turek

Advertorial article in the Cardiovascular News Issue 52 – Feb 2019.

Early results for HAART 200 and HAART 300 Aortic Annuloplasty Devices are encouraging

The Duke Children’s Pediatric & Congenital Heart Center (Duke University Medical Center, Durham, USA) treats the entire spectrum of patients with complex congenital heart disease. In this article, Cardiovascular News focuses on how the centre manages patients with congenital aortic valve disease—specifically, their use of the HAART 200 and HAART 300 (both BioStable) internal aortic valve annuloplasty rings.

[Read the entire article on Cardiovascular News Issue 52 – Feb 2019.]

Cardiovascular News is a news source for cardiovascular research and conference updates.

Double Valve Repair with Dr. George Stavridis

Abstract / video posted on the website.

Abstract: “Double Valve Repair for Marfan Aortic Root Aneurysm and Bileaflet (Barlow’s) Mitral Valve”[1]

Objective: Repair of simultaneous complex aortic and mitral valve defects in patients with Marfan syndrome can be difficult. This video illustrates a double valve repair using two remodeling annuloplasty rings, as a technical simplification for simultaneous reconstruction. [Read more from the CTSNet website]

  1. Stavridis GT, Kantidakis G, Kaminiotis VV, Vassili M-I, Rankin JS. Double Valve Repair for Marfan Aortic Root Aneurysm and Bileaflet (Barlow’s) Mitral Valve. December 2018. doi:10.25373/ctsnet.7390304. is the most comprehensive, heavily trafficked, and reliable online source of information about cardiothoracic surgery available worldwide, and its online community of cardiothoracic surgeons is the largest in the world. A not-for-profit organization, CTSNet is jointly overseen by The Society of Thoracic Surgeons (STS), the American Association for Thoracic Surgery (AATS), and the European Association for Cardio-thoracic Surgery (EACTS).

Advantages of Aortic Valve Repair with Dr. Lawrence Wei

Video posted on the website.

This video shows the advances in aortic valve repair for aortic stenosis, using annuloplasty rings, and aortic regurgitation, using the Ozaki procedure, from Dr Lawrence Wei, cardiac surgeon at WVU Heart & Vascular Institute.

Surgeon Q&A: Aortic Valve Repair Innovations with Dr. Vinay Badhwar

Video posted on the website.

Learn about the newest innovations in aortic valve repair surgery for patients with aortic stenosis and aortic regurgitation from Dr. Vinay Badhwar, cardiac surgeon at West Virginia University Medicine. is a website founded by Adam Pick, a former, double heart valve surgery patient, whose mission is to educate and empower patients, their families and friends — from diagnosis to recovery. is a tremendous resource and has “helped over 10 million people better understand their valvular disorders and their treatment options.[1]”


About BioStable Science & Engineering
BioStable Science & Engineering is a cardiovascular device company focused on developing and commercializing proprietary valve repair technologies that provide an alternative to valve replacement for patients with aortic valve disease. The company’s HAART Aortic Repair Technologies are designed to simplify and standardize aortic valve repair, enabling surgeons to offer the recognized clinical benefits of valve repair to patients undergoing surgical correction of aortic insufficiency or aortic root aneurysm.

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